Make = create
Ex: make dinner
Ex: make a dress
Ex: make a webpage <create as in design>
Ex: make the bed <create a comfortable place>
Ex: make a joke <as in tell a joke, meaning create laughter>
Ex: make a phone call <create a connection>

Do = physical work
Ex: Do your homework
Ex: Do the dishes
Ex: Do housework
Ex: Do a song <synonymouos with sing a song>